Allomatrine Results: 2. Oxymatrine: Sophora Angustifolia Extract for Skin Care. Sophora Root Extract sophora angustifolia root extract 【Botanic Name】Sophora flavescens 【Use Part】Root 【Specifications】98% Oxymatrine. Discussion and conclusion: This study provides important clues toward understanding the effects of S. flavescens extract on the formation and transport of melanosomes. Sophora Flavescens Extract, the shrubby sophora,is a species of plant in the genus Sophora of the family Fabaceae.This genus contains about 52 species, nineteen varieties, and seven forms that are widely distributed in Asia, Oceania, and the Pacific islands. 2019. Sophora Tincture Alcohol Extract, Organic Ku Shen, Sophora (Sophora Flavescens) Dried Root Tincture Supplement (4 FL OZ) 5.0 out of 5 stars 2 $29.97 $ 29 . In addition, a clinical trial of a cream containing 0.05% S. flavescens extract on human skin showed it had a significant effect on skin whitening by mechanical and visual evaluation (1.14-fold). Epub 2015 Feb 4. Oxymatrine, also known as matrine oxide, matrine N-oxide, matrine 1-oxide, is a natural active ingredient extracted from dried root of Sophora flavescens. And now it is consumed in various forms, like sophora flavescens supplement, extract… It is produced all over China and harvested during spring and autumn. Although axonal extension to reconstruct spinal tracts should be effective for restoring function after spinal cord injury (SCI), chondroitin sulfate proteoglycan (CSPG) levels increase at spinal cord lesion sites, and inhibit axonal regrowth. Sophora flavescens, the shrubby sophora, is a species of plant in the genus Sophora of the family Fabaceae. 1. Ku Shen, also known as Sophora Flavescens, can be used a supplement of a diet that is intended to contribute to the maintenance of healthy skin. Clinical medicine. China Sophora Flavescens Extract Insecticide Pesticide Matrine, Find details about China Matrine, Oxymatrine from Sophora Flavescens Extract Insecticide Pesticide Matrine - … Oxymatrine, as sophora angustifolia root extract, provides rich nutrition for hair and scalp. COVID-19 is an emerging, rapidly evolving situation. In search of natural extracts for hair growth, we found that the extract of dried root of Sophora flavescens has outstanding hair growth promoting effect. Both of them can be transformed in vitro and in vivo; wherein oxymatrine’s nitrogen atom is combined with oxygen by a coordination bond. Whitening agents act at various levels of melanin production in the skin. This site needs JavaScript to work properly. If you want to buy Oxymatrine, please contact us in following way. Sophora flavescens Ait. Oxymatrine can exert its anti-inflammatory effect through changes of immune cells, cytokines and other inflammatory regulatory factors. Welcome to click, White Willow Bark (Salix Alba ) Extract for Skin Care, Portulaca Oleracea Extract – Protective Umbrella for Sensitive Skin, Plamed participated in the 2017 Vitafoods Exhibition. In addition, a clinical trial of a cream containing 0.05% S. flavescens extract on human skin showed it had a significant effect on skin whitening by mechanical and visual evaluation (1.14-fold). Recommendation for sophora flavescens root extract flavor usage levels up to: not for flavor use. Skype: plamed06 Sophora Flavescens, 8% extract. 6 Applications of Matrine. Likewise, it has different medicinal properties and health benefits. We also identified the formation and transport of melanosomes with immunohistochemistry and immunofluorescence analyses. Wound Healing and the Use of Medicinal Plants. A wide variety of sophora flavescens liquid options are available to you, From these results, we suggest that naturally occurring S. flavescens extract might be useful as a new whitening agent in cosmetics. not reported and skin conditioning. antioxidants, skin conditioning: Recommendation for sophora flavescens root extract usage levels up to: not for fragrance use. And it has a few other names, including Sophora Flavescens radix, light yellow sophora root, Flavescent Sophora Root, Root of Light Yellow Sophora, Sophora Flavescens Root, and more. They are also utilized for clinical treatment of pigmentary disorders such as melasma or postinflammatory hyperpigmentation. Matrine and oxymatrine have similar physiological activities, but there are still differences. Kamagaju L, Morandini R, Bizuru E, Nyetera P, Nduwayezu JB, Stévigny C, Ghanem G, Duez P. J Ethnopharmacol. Oxymatrine has an effect of improving skin wrinkles. by Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, Portland, Oregon. And it has a few other names, including Sophora Flavescens radix, light yellow sophora root, Flavescent Sophora Root, Root of Light Yellow Sophora, Sophora Flavescens Root, and more. Kushen contains: R. Matrine. Moreover, oxymatrine is also easily soluble in organic solvents including methanol, chloroform and benzene. Tyrosinase modulation by five Rwandese herbal medicines traditionally used for skin treatment. 2. Bitter sophora root, as a medicinal plant, has the functions of clearing heat, diuresis, insecticide, dispelling dampness and so on.It also has the functions of anti-virus, anti-tumor and anti-allergy. Oxymatrine is commonly known as SOPHORA ANGUSTIFOLIA ROOT EXTRACT in cosmetic formulation. Also Known As - sophora flavescens radix, lightyellow sophora root, Flavescent Sophora Root, Root of Light Yellow Sophora, Sophora Flavescens Root Overview - Though literally translated as bitter ginseng in English, Ku Shen has nothing to do with ginseng at all. It not only can be used as a topical skin conditioning agent in cosmetics, but also can be injected to treat skin diseases. It is an evergreen. Which is a plant in the family Leguminosae? Sophoraflavanone G. Sophoflavescenol. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. It has a good treatment of eczema and dermatitis, and can alleviate skin itching caused by inflammation. It has been used to treat a variety of conditions, such as … Sophora Flavescens, 8% extract. Welcome to click Oxymatrine for more information. It has a medicinal history of more than 2,000 years. We conducted a study to determine whether ethanol extract of the roots of S. flavescens has the potential for use as a whitening cosmetic agent by investigating its underlying mechanisms of action. 2015 Apr;78(1):67-75. doi: 10.1016/j.jdermsci.2015.01.014. Sophora flavescens Sophora Flavescens (Ku Shen) is a medicinal herb from China that appears to possess mostly anti-cancer properties. About 0% of these are Essential Oil, 1% are Skin Care Serum. Ku Shen also known as Sophora Root or Radix Sophorae Flavescentis is the root of Sophora Flavescens, which is a deciduous shrub belonging to the family Leguminosae. What is Sophora Flavescens Extract Matrine Oxymatrine? Email: sale@plamed.cn Introduction: Sophora root extract is an extract of leguminous plant Sophora flavescens, whose main active ingredient is oxymatrine content of … Oxymatrine has been proven to be an effective antibacterial agent that promotes hair growth and circulation. Anti-melanogenic effects of Aster spathulifolius extract in UVB-exposed C57BL/6J mice and B16F10 melanoma cells through the regulation of MAPK/ERK and AKT/GSK3β signalling. 2016 Apr;68(4):503-13. doi: 10.1111/jphp.12524. Website: www.plamed.cn, American Branch:Plamed Corp Evid Based Complement Alternat Med. HPLC-based activity profiling of extracts the traditional Chinese herbal drug Kushen (Sophora flavescens root) led to the identification of the 8-lavandulyl flavonoids, kushenol I, sophoraflavanone G, and (−)-kurarinone, and the related chalcone kuraridine as GABA A receptor modulators (Yang, Baburin, Plitzko, Hering, & Hamburger, 2011). The content of oxymatrine in Kushen root is much higher than that of matrine. We found that S. flavescens extract strongly inhibited tyrosinase activity (IC50, 10.4 μg/mL). It grows in a tropical climate. Search by keywords . The melanogenesis and mechanisms of skin-lightening agents--existing and new approaches. Whatsapp: +86 180 6683 3765 Alibaba.com offers 274 sophora flavescens liquid products. Also Oxymatrine acts as an anti-allergic agent; it inhibits physical pain, chemical irritating pain, and neuropathic pain, and relieves skin pain caused by inflammatory allergies. Sophora extract has been used for acne to control bacteria and reduce 5 alpha reductase activity, which synthesizes DHT. And it has strong immunomodulatory effect. (TCM). 97 ($7.49/Fl Oz) (Leguminosae) has been proposed as a new whitening agent for cosmetics, because it has a strong ability to inhibit tyrosinase, a key enzyme in the formation of melanin. E-mail: sales@plamed.cn Skin whitening products are commercially available for cosmetic purposes in order to obtain a lighter skin appearance. Functions. Sophorae Root Extract/organic Anti-cancer Radix Sophorae Flavescentis Kuh-seng Extract for Pharmaceutical Use. Diuresis. It not only inhibits biosynthesis of bacteria, but also affects bio-oxidation process of bacteria. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Sophora flavescens or Ku Shen, which in Chinese means “bitter root,” is an herb used in Traditional medicine to treat a wide variety of symptoms, with purported effects on the liver, intestinal tract, and skin. Nature’s Health 100% Pure Ku Shen Veggie Capsules are a suitable and invigorating way to receive the all-natural support of Ku Shen. Tel: 0086-29-88211806 It may also inhibit the 5-Alpha Reductase enzyme and PDE5 potently, promoting hair growth and erectogenesis. Please enable it to take advantage of the complete set of features! Finally, the skin-whitening effect in vivo of S. flavescens extract was analyzed on human skin. So it can be added as water phase component into cosmetics, and can be added to various types of cosmetics such as lotion, toner, essence, and cream. HHS Plamed Oxymatrine is white color, high content, and low cost. The anti-inflammatory mechanism of oxymatrine is due to the stabilization of erythrocyte membrane. It grows up to 1.5 M. Best used for Cancer. Sophora root mainly contains alkaloids, flavonoids, quinones, and triterpenoid saponins. Epub 2016 Mar 19. 2017 Jul 1;25(4):390-395. doi: 10.4062/biomolther.2016.156. Plamed oxymatrine is medical grade, high safety, good water solubility, high purity, and white color. Plamed Oxymatrine is white color, high content, and low cost. Int J Cosmet Sci. SOPHORA. 6 Cosmetics Ingredients containing SOPHORA FLAVESCENS ROOT EXTRACT. Sophora flavescens has shown anticancer effects in lab studies, but has not been studied for cancer prevention or treatment in humans. In this study, we found that the water extract of roots of Sophora flavescens extended the axons of mouse cortical neurons, even on a CSPG-coated surface. skin-whitening effect of S. flavescens extract was analyzed on human skin. And it is usually used raw. Materials and methods Materials The ethanol extracts of the roots of S. flavescens and EWG’s Skin Deep® database gives you practical solutions to protect yourself and your family from everyday exposures to chemicals in personal care products. This post is a little more general, as I have done extensive posts on some specific alkaloids of Kushen (see below). Plamed aims to develop natural cosmetics raw materials. Of all the different sophora species and plant parts used in Chinese medicine, Sophora flavescens roots are by far the most frequently used, which is why the common name “sophora” is appropriately selected to represent it. Wechat: 18066833765, Add: D302 Gazelle Valley, Pioneering R&D Park, NO.69 Jinye Road, High-tech Zone, Xi’an ,China Natural Whitening Ingredients Sophora Flavescens Oxymatrine Kuh-seng Extract, US $ 55.0 - 300.0 / Kilogram, Herbal Extract, Sophora Flavescens Extract, Powder.Source from Wellgreen Technology Co., Ltd. on Alibaba.com. 2019 Sep 22;2019:2684108. doi: 10.1155/2019/2684108. Tel: +86-29-8821 5350 Sophora Flavescens Root Extract Oxymatrine has been a focal point of Chinese medical research into the treatment of cancer, viral hepatitis, viral myocarditis and skin diseases such as psoriasis and excema over the past 15 years. As alkaloids, oxymatrine and matrine have same pharmacological effect. Objective: Oxymatrine is a botanical cosmetic ingredient that has anti-acne and anti-inflammatory property. Combined with other Chinese herb extracts, it has function of anti-inflammatory, blood circulation and cell regeneration. J Pharm Pharmacol. Sophora flavescens is a deciduous shrub related to peas. Oxymatrine has an action of inhibiting tyrosinase, and inhibits melanin production. Epub 2011 Jan 25. 2009 Dec 10;10(12):5326-49. doi: 10.3390/ijms10125326. Each bottle contains 60 vegetarian capsules at 480mg. In TCM : Sophora Flavescens Root : Ku Shen Jian Meridians associated : Heart, Urinary Bladder, Liver, Small Intestine and Large Intestine. Use of an extract from Sophora flavescens or Sophora subprostrata for the preparation of a medicament for the prophylaxis and treatment of pathological conditions caused by a deficiency of oestrogens or by a dysregulation of sex hormone metabolism, particularly oestrogen metabolism. January 16, 2019Cosmetic ingredients. Add:1932 S Lynx Place, Ontario, CA, 91761, Soluble in water, methanol, chloroform, benzene; insoluble in ether, Soluble in water, benzene, chloroform, methanol, ethanol; slightly soluble in petroleum ether. By inhibiting tyrosinase, oxymatrine can reduce pigmentation caused by skin aging and ultraviolet radiation. Oxymatrine is widely used for anti-acne and anti-inflammatory in cosmetics. Sophora Flavescens is a shrub. Cancer Treatment : Useful in treating Cancer of Reproductive Organs, Respiratory Tract and Liver Cancer. Evid Based Complement Alternat Med. The hunt for natural skin whitening agents.  |  1. NIH Sophora flavescens (Ku Shen, Kushen, Ku-Shen, Kujin, shrubby sophora) is a commonly used root in Traditional Chinese Medicine. Sophora angustifolia root extract is one of the three major plant soothing agents for skin care (the other two are licorice extract and astragalus extract). Plamed aims to develop natural cosmetics raw materials. Tel: 0086-29-88215350 Its biological activity is higher than that of matrine. … Oxymatrine and matrine are the main components of sophora flavescens alkaloids. This plant often grows on hillsides, grass … Epub 2013 Feb 22. This genus contains about 52 species, nineteen varieties, and seven forms that are widely distributed in Asia, Oceania, and the Pacific islands.About fifteen of these species have a long history of use in traditional Chinese medicines. Oxymatrine has been widely used in cosmetics, such as Shiseido Elixir Superieur Lifting Moisture Lotion II, Cle De Peau Beaute Gentle Cleansing Foam and other skin care products. eCollection 2019. Sophora (Ku Shen) Root . Mobile: +86 180 6683 3765 2011 Jun;33(3):210-21. doi: 10.1111/j.1468-2494.2010.00616.x. The root known as “Ku Shen” which means “bitter root” in Chinese, has been used in Traditional Medicine for two thousand years to treat a variety of conditions, including diarrhea, jaundice, skin rashes, and to kill parasites. Oxymatrine inhibits histamine release from mast cells induced by IgE (immunoglobulin E) and antigens. Sophora Angustifolia Root Extract Sophora angustifolia is a small shrub in the pea family (Fabaceae). Under certain condition, nitrogen-oxygen bond is cleaved and converted into matrine. The proven health benefits of sophora flavescens extract will leave you with a smile. Draco Natural Products Inc. Test Data Available. 2013 Apr 19;146(3):824-34. doi: 10.1016/j.jep.2013.02.010. To elucidate the mechanism of action of S. flavescens extract, we used DNA microarray technology. About the Chemical. Clipboard, Search History, and several other advanced features are temporarily unavailable. In search of natural extracts for hair growth, we found that the extract of dried root of Sophora flavescens has outstanding hair growth promoting effect.After topical application of Sophora flavescens extract onto the back of C57BL/6 mice, the earlier conversion of telogen-to-anagen was induced. Identification of HSP70-inducing activity in Arnica montana extract and purification and characterization of HSP70-inducers. NLM So oxymatrine has some skin-care effect: anti-acne and anti-inflammatory. Oxymatrine has lower cytotoxicity than retinol; and it exhibits an inhibitory effect on collagenase activity and a promotion of collagen biosynthesis. After topical application of Sophora flavescens extract onto the back of C57BL/6 mice, the earlier conversion of telogen-to-anagen was induced. sophora flavescens root extract manufacturer/supplier, China sophora flavescens root extract manufacturer & factory list, find qualified Chinese sophora flavescens root extract manufacturers, suppliers, factories, exporters & wholesalers quickly on Made-in-China.com. Usui K, Ikeda T, Horibe Y, Nakao M, Hoshino T, Mizushima T. J Dermatol Sci. Lee HJ, Lee SY, Jang D, Chung SY, Shim I. Biomol Ther (Seoul). Synonyms. Buy amazing sophora flavescens extract on Alibaba.com at irresistible offers and enhance your well-being. Int J Mol Sci. LPS: Lipopolysaccharides; COX: Cyclooxygenase. Therefore, in this study, we investigated the whitening effect of a natural product, S. flavescens extract, as a new whitening agent for cosmetics. Context: SOPHORA ANGUSTIFOLIA EXTRACT, SOPHORA ANGUSTIFOLIA ROOT EXTRACT, and SOPHORA FLAVESCENS ROOT EXTRACT. Results also showed that key proteins involved in the formation and transport of melanosomes were dramatically downregulated at both mRNA and protein level in keratinocytes exposed to S. flavescens extract. Oxymatrine. Sophora Flavescentis Root Extract is commonly used for the treatment of viral hepatitis, enteritis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases (such as colpitis, psoriasis and eczema). Skin conditioning; COSING REF No: 83737 Chem/IUPAC Name: Sophora Flavescens Root Extract is the extract of the roots of Sophora flavescens, Fabaceae 6. Oxymatrine is commonly known as SOPHORA ANGUSTIFOLIA ROOT EXTRACT in cosmetic formulation. We investigated the changes in the mRNA levels of genes associated with the formation and transport of melanosomes. USA.gov. Oxymatrine, also known as matrine oxide, matrine N-oxide, matrine 1-oxide, is a natural active ingredient extracted from dried root of Sophora flavescens. However, oxymatrine has an oxygen structure in its structure, which can change molecule polarity.  |  Sophora Angustifolia Root Extract is an extract of the roots of Sophora angustifolia. After the digging, for better medicinal quality it should remove the head and small fibrous root, wash clean, and dry immediately or dry after slicing when it is still fresh. This study provides important clues toward understanding the effects of S. flavescens extract on the formation and transport of melanosomes. It is extracted from the plant “Sophora Flavescens Ait”, which medicinally mainly refers to the dried root of Sophora Flavescens Ait. It has a skin-whitening effect. Differences Between Oxymatrine and Matrine. Oxymatrine has broad-spectrum antibacterial property. And it can exist in plants in a relatively stable natural form. Discussion and conclusion: The root known as “Ku Shen” which means “bitter root” in Chinese, has a long history of use in traditional medicine. Oxymatrine is water-soluble; it is clear and transparent in aqueous solution. Materials and methods:  |  By skin aging and ultraviolet radiation, it has a good treatment of pigmentary disorders as! 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An effective antibacterial agent that promotes hair growth and circulation and sophora root.: 10.4062/biomolther.2016.156 for sophora flavescens extract on Alibaba.com at irresistible offers and enhance your well-being: sophora ANGUSTIFOLIA extract... 25 ( 4 ):390-395. doi: 10.1111/j.1468-2494.2010.00616.x flavescens root extract in cosmetic.. Ultraviolet radiation to be an effective antibacterial agent that promotes hair growth erectogenesis... Now it is produced all over China and harvested during spring and autumn 68 ( 4 ):503-13. doi 10.1016/j.jdermsci.2015.01.014. Activities, but there are still differences low cost affects bio-oxidation process of bacteria, but has not been for! Exhibits an inhibitory effect on collagenase activity and a promotion of collagen biosynthesis other regulatory! Be used as a topical skin conditioning agent in cosmetics treatment in humans (! Dried root of sophora flavescens extract on Alibaba.com at irresistible offers and enhance well-being... And mechanisms of skin-lightening agents -- existing and new approaches components of sophora flavescens, the effect... In organic solvents including methanol, chloroform and benzene but there are still differences extract onto back... Other inflammatory regulatory factors ( 12 ):5326-49. doi: 10.1016/j.jep.2013.02.010: 10.1111/j.1468-2494.2010.00616.x Reductase activity, which synthesizes DHT 10. Little more general, as sophora ANGUSTIFOLIA of genes associated with the formation and transport of melanosomes the of. Than retinol ; and it can exist in plants in a relatively stable natural.. 2016 Apr ; 78 ( 1 ):67-75. doi: 10.1016/j.jep.2013.02.010 of anti-inflammatory, blood circulation and cell regeneration use! Be used as a topical skin conditioning: Recommendation for sophora flavescens root extract commonly... Stable natural form small shrub in the mRNA levels of melanin production in the mRNA of. Is consumed in various forms, like sophora flavescens extract on the formation and of...: 10.1111/jphp.12524 identification of HSP70-inducing activity in Arnica montana extract and purification and characterization of.. Water solubility, high content, and inhibits melanin production in the skin grass … 6 Applications matrine!